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Find patient medical information for Modafinil (Provigil) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant medication used to treat narcolepsy, sleep apnea, and shift work sleep disorder. [3][7][15] It is taken by mouth. [3][7] Modafinil is a first-line treatment for narcolepsy in the United States and Europe. [16][17] The mechanism of action is not fully understood, but modafinil acts mainly as … Provigil (modafinil) is used for excessive sleepiness caused by narcolepsy, sleep apnea, and shift work. Learn about side effects, warnings, dosage, and more. Modafinil (Provigil) is a medication that treats excessive tiredness caused by narcolepsy, sleep apnea and shift work sleep disorder. 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